This study sought to determine the correlation between transportation system development and the performance of the manufacturing sector in Kenya. This is because; in Kenya contribution of the manufacturing sector to the country’s GDP has been decreasing for the last three years posting 8.4%, 7.9%, and 7.6% in 2019, 2020, and 2021 respectively. The study used primary and secondary data to achieve this objective. Data was collected using a questionnaire, documentary analysis guide, and group interview schedule. The data was sourced from 254 managers of manufacturing firms in Kenya, selected by purposive, stratified, and quota sampling. The data were analyzed using a t-test, one-way ANOVA, regression, and correlation analysis. Descriptive statistics namely mean frequencies, percentages, and standard deviations were also used. Qualitative data was analyzed using themes. The findings revealed that the transport system had a positive significant relationship with the performance of the manufacturing sector in Kenya. The null hypothesis was rejected. The challenges facing manufacturers included high taxation, low demand, and transport issues.