The main objective of the study was to assess factors affecting the effectiveness of supply chain management practices in Kenyan public sector case of Ministry of Finance with the aim of assessing the effect of supplier relationship on the effectiveness of supply chain management practices. The study adopted a descriptive case research design with study population of 120 management staff working at the Ministry of finances’ procurement, finance and administration departments from which a sample size of 60 respondents was drawn. Questionnaires were used for data collection and descriptive statistics data analysis method was applied to analyze data aided by Statistical Package for Social Sciences. The study identified that lack of supplier relationship management strategies lowered the effectiveness of supply chain management functions. The study recommended application of supplier collaboration strategies.