Chemical investigation of CH2Cl2 and MeOH extracts of Conyza floribunda have led to the isolation of (24S)-ethylcholesta-5, 22E, 25-trien-3-O-glucosyl (1” 4’)-rhamnoside (1), (24S)-ethylcholesta-5,25-dien-3-O- -glucoside (2), cyasterone (3), stigmasta 5, 22-dien-3-acetate (4), stigmasta 5, 22-dien-3-ol (5), spinasta 7, 22-dien-3-ol (6), 3-oxofriedooleanane (7), 3-hydroxyfriedooleanane (8), 3-acetoxyfriedooleanane (9), betullinic acid (10), quercetin 3-O- -glucoside (11), quercetin (12), myricetin (13) and kaempferol (14). Their structures were determined using spectroscopic and physical methods as well as comparison with data available in the literature.