Heavy metal pollution in water poses a risk to both drinking water and fish consumed by people. This study aimed to assess how various heavy metals are distributed among different fish species. The study measured the levels of copper, zinc, lead, nickel, chromium, barium, arsenic, and cadmium in the tissues of three different fish species from Lake Turkana. These species – Synodonis catfish (Synodontis schall), Nile tilapia (Oreochromis niloticus) and Nile perch (Lates niloticus) were collected from the Kalokol and Longech fish markets in June 2022. Heavy metal concentrations in the fish muscles were determined using an Agilent 4210 Microwave Plasma Atomic Emission Spectrometer (MP-AES). The concentrations of most metals were consistently highest in Nile Perch followed by Catfish, and then Nile tilapia. For instance, the average concentration of zinc for the two markets was: Nile perch (0.769 ± 0.057 mg/kg), catfish (0.559 ± 0.084 mg/kg) and Nile tilapia (0.327 ± 0.041 mg/kg). Overall, the heavy metal concentrations in all the sampled fish were low and well within the World Health Organization's established minimum permissible levels. Non-carcinogenic health risks were evaluated by calculating the Estimated Daily Intake, Target Hazard Quotient, and Hazard Index. Nile perch had the highest hazard index (0.4099500) followed by catfish (0.3690927), and Nile tilapia (0.3448890). The fish from Lake Turkana are safe for consumption. Continued monitoring is recommended to ensure heavy metals remain within safe limits.