Over the years, new technologies have been tested and introduced to control Striga in maize producing areas but adoption has remained low. The study done in 2013, determined the demographic and socioeconomic factors that influenced the adoption of Striga control technologies in Kisumu West, Bumula and Teso South sub counties of Western Kenya. Through Multi stage sampling technique, 40 households were selected per sub county for questionnaire administration; to gather information on demographic profiles of the sample population, type of fertilizer and seed variety used, income of the household, source of credit facilities and challenges faced in weed control. Chi square test at P<0.05 and logistic regression analysis, using R software was used to determine the relationship between demographic and socioeconomic factors and uptake of Striga control technologies. Farmers cited high cost, poor availability of improved varieties and lack of adequate knowledge as reasons for non-adoption of the Striga control strategies. Farmer’s age, education, land size and hiring of labour were found to significantly influence the adoption of the Striga control technologies. The low levels of adoption of modern technology indicate that they were not meeting farmers’ expectations, thus, researchers should put into consideration farmers’ education, age, land size and ability to high labour in their planning for an informed technology adoption. In addition, alternative options should be extended to farmers who are not able to use expensive technologies.