This paper investigates the application of large-scale solar photovoltaic (SPV) system for voltage stability improvement of weak national grids. Large-scale SPV integration has been investigated on the Nigerian power system to enhance voltage stability and as a viable alternative to the aged shunt reactors currently being used in the Nigerian national grid to mitigate overvoltage issues in Northern Nigeria. Two scenarios of increasing SPV penetration level (PL) are investigated in this work, namely, centralized large-scale SPV at the critical bus and dispersed large-scale SPV across the weak buses. The voltage stability of the system is evaluated using the active power margin (APM) also called megawatt margin (MWM) derived from Active Power–Voltage (P–V) analysis, the reactive power margin (RPM) and the associated critical voltage–reactive power ratio (CVQR) index obtained from Reactive Power–Voltage (Q–V) analysis. All simulations are carried out in DIgSILENT PowerFactory software and result analyses done with MATLAB. The results show that with centralized SPV generation for the case study system, the highest bus voltage is able to fall within acceptable limits at 26.29% (1000 MW), while the dispersed SPV achieves this at 21.44% (800 MW). Also, the dispersed SPV scenario provides better voltage stability improvement for the system as indicated by the MWM, RPM and the CVQR index of the system. Therefore, this work provides a baseline insight on the potential application of large-scale SPV in weak grids such as the Nigerian case to address the voltage stability problems in the power system while utilizing the abundant solar resource to meet the increasing energy demand.