School of Health Sciences (JA)
Browse by
Recent Submissions
-
Red cell allo- and autoimmunisation in transfused sickle cell and cancer patients in Kenyatta National Hospital, Nairobi, Kenya
(African journal of laboratory medicine, 2015)Background: Currently, no data are available on the prevalence of red blood cell (RBC) antibody formation amongst Kenyan patients with multiple transfusion needs, such as patients with sickle cell disease (SCD) or ... -
Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads
(International Journal of Molecular Sciences, 2019)Viral infections and reactivations remain a serious obstacle to successful hematopoietic stem cell transplantation (HSCT). When antiviral drug treatment fails, adoptive virus-specific T-cell transfer provides an effective ... -
CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virusassociated lymphoproliferation
(Journal for ImmunoTherapy of Cancer, 2020)Background Immunosuppressive therapy or T-cell depletion in transplant patients can cause uncontrolled growth of Epstein-Barr virus (EBV)-infected B cells resulting in post-transplant lymphoproliferative disease (PTLD). ... -
Variances in Antiviral Memory T-Cell Repertoire of CD45RA- and CD62L-Depleted Lymphocyte Products Reflect the Need of Individual T-Cell Selection Strategies to Reduce the Risk of GvHD while Preserving Antiviral Immunity in Adoptive T-Cell Therapy
(Journal of Transfusion Medicine and Hemotherapy,, 2021)Introduction: Viral infections and reactivations still remain a cause of morbidity and mortality after hematopoietic stem cell transplantation due to immunodeficiency and immunosuppression. Transfer of unmanipulated ... -
Enhancement of Antiviral T-Cell Responses by Vitamin C Suggests New Strategies to Improve Manufacturing of Virus-Specific T Cells for Adoptive Immunotherapy
(MDPI, 2022)Allogeneic and autologous transplantation of hematopoietic stem cells (HSCT) are being routinely used to treat patients with leukemia and lymphoma. Due to the required immunosuppression after stem cell transplantation, ... -
Selected haematological markers and C-reactive protein, not AGTR1 SNP, are associated with essential hypertension in Tharaka Nithi County,
(Asian Journal of Medicine and Health, 2023)Background: Essential Hypertension (EH) accounts for majority of hypertension cases globally. Genetic factors along with haematologicaland biochemical changes may underlie EH and these have not been well ... -
Effect of female partner-led brochures method on knowledge and intention for prostate cancer screening among men in Kiambu County, Kenya
(International Journal of Community Medicine and Public Health | December 2024| Vol 11 | Issue 12 Page 4617International Journal of Community Medicine and Public Health, 2024)Background:Prostate cancer (PC) is a problem of public health concern globally. The problem is further complicated by the low rates of screening which results in late detection of the disease. Further, the misconception ... -
Leveraging female partner influence in health interventions: a study on prostate cancer screening uptake among men in rural Kiambu County, Kenya
(International Journal of Community Medicine and Public Health, 2024)Background:Globally, prostate cancer is the second most common cancer affecting men, with considerably high fatality rates. The aim of this study was to assess the effect of a female partner-led ... -
Assessment of Use of Medical Forensic Evidence in Investigation and Prosecution Process of Defilement Perpetrators, A Case Study of Ruiru Sub-County, Kenya
(International Journal of TROPICAL DISEASE& Health, 2023)Background: Defilement has been recognized as one of the crimes in which such a ceiling in evidential presentation is critical. According to WHO statistics, More than 95 million children are ... -
Assessment of Factors Influencing Utilization of Reproductive Health Services for Adolescents and Youth in Samburu County, Kenya
(International Journal of TROPICAL DISEASE & Health, 2023)Background: Globally, around 16 million teenagers give birth each year, with 95% of them coming from upcoming nations in developing nations like Kenya, youths deal with a variety of sexual and reproductive health issues. ... -
Risk Factors Associated with Diabetic Retinopathy among Patients Aged 50-75 Years Attending Diabetic Clinic at Mbagathi Hospital Nairobi County, Kenya
(International Journal of TROPICAL DISEASE & Health, 2023)Background: According to research, nearly 60% of persons with type 1 diabetes are likely to experience diabetes retinopathy after 20 years after the initial diagnosis of diabetes type 1. Nearly 40 % of all persons with ... -
Factors Influencing Uptake of Cervical Cancer Screening among Rural Women in Webuye East Sub -County, Kenya
(Factors Influencing Uptake of Cervical Cancer Screening among Rural Women in Webuye East Sub -County, Kenya, 2019)Aims:The study sort to determine factors influencing the uptake of cervical cancer screening services among rural women aged 18-69 years in Webuye East Sub-County, Kenya. Study Design:We conducted a cross-sectional ... -
Perspectives of healthcare workers on chemotherapy treatment in selected facilities in Kenya
(International Journal of Community Medicine and Public Health, 2024-03)Healthcare workers are better placed to recognize the drivers of the cancer health care experience by patients, an important ingredient in shaping the realization of the third pillar of the Kenya National Cancer Control ... -
Factors influencing availability of tracer essential medicines in selected health facilities in Nyeri County, Kenya
(International Journal of Community Medicine and Public Health, 2021)Background:Tracer essential medicines are drugs which fully fulfil a population’s health requirements and ought to be always available allowing for a properly functioning health system all the time. They should ... -
Level of awareness of the benefits,socio-demographic and cultural factors influencing exclusive breastfeedingamong mothers attending MCH clinic in Tudor sub county hospital
(International Journal of Community Medicine and Public Health, 2021)Background:Knowledge of exclusive breastfeeding (EBF) among women is essential when promoting optimal breastfeeding practices.Breastfeeding is recommended for the first six months of life and ... -
Activation in Cancer Survivorship in Kenya: Results of A Cluster-Randomized Trial
(Journal of Clinical Nursing & Reports, 2024-07)Introduction: Kenya’s cancer situation, as in the rest of the developing world, is marred by treatment access deficiencies arising from multiple foci in the continuum of health care that make survival difficult. These ... -
Effectiveness of Short Message Service Support on Adherence to Chemotherapy Treatment among Patients Attending Cancer Treatment Facilities in Kenya
(Open Journal of Nursing,, 2024)Introduction: Cancer is a chronic debilitating disease that unnerves patients, communities, and nations. At some point in cancer patient’s disease experience, chemotherapy is used, and the patient is expected to adhere ... -
Socio-demographicfactorsinfluencingpracticeandawarenessofexclusive breastfeedingbenefitsamongwomenofreproductiveageattendingmaternal and child healthclinicintudorsubcountyhospital
(nternational Journal of Community Medicine and Public Health, 2021)Background:Knowledge of exclusive breastfeeding (EBF) among women is essential when promoting optimal breastfeeding practices. Breastfeeding is recommended for the first six months of life ... -
Health Behaviour among Nurses Working in Public Hospitals in Kakamega County, Kenya
(Nursing Research and Practice, 2017)Health behaviour refers to actions undertaken by a person who perceives self to be ill for the purpose of finding an appropriate remedy. Nurses as gate keepers of health are expected to seek formal treatment when they are ... -
Factors Associated with Non-adherence to Anti-Retroviral Therapy among Clients in Lodwar County and Referral Hospital, Turkana County, Kenya
(British Journal of Medicine and Medical Research, 2020)Patient, Health-facility and Socio-cultural related factors associated with non-adherence have contributed to poor management of ART among HIV/AIDS clients. In Lodwar County and Referral Hospital, Turkana County, ...
RSS 1.0