School of Pure, Applied and Sciences (JA)
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The Great Mimicker: Chronic Thromboembolic Pulmonary Hypertension
(IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 2025)Chronic thromboembolic pulmonary hypertension (CTEPH) is a sub-category of pulmonary hypertension that is unique from other forms of pulmonary hypertension with regards to its pathogenesis, patient characteristics and ... -
Efficacy of Plant-based Repellents Against Anopheles Mosquitoes: A Systematic Review
(Biomedical Sciences, 2020)Mosquitoes are usually targeted using insecticides, insect growth regulators, and microbial agents. Indoor residual spraying and insecticide-treated bed nets. However, these strategies have negative effects on human health, ... -
Phytochemicals Extraction in Craterostigma Plantagineum Hoscht: Aqueous and Ethanol Solvents
(Scholars International Journal of Anatomy and Physiology, 2023)Phytochemicals are plant bioactive compounds that are produced for their protection with some having medicinal value. Craterostigma plantagineum hoscht is a plant that is purported to have medicinal value and is used for ... -
Malignant Small Round Cell Tumor: A Rare Aggressive Malignancy-Case Report
(INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH, 2023)Background: Malignant Small round Cell Tumor (MSRCT) is very rare group of tumors. Malignant cells have similar histologic appearance making it difficult to distinguish one from another, and poses a diagnostic challenge ... -
Association between Serum Total Bilirubin Level and Clinical Outcome of COVID-19 Infection: Protective Role of Bilirubin
(Scholars International Journal of Anatomy and Physiology, 2023)Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) causes covid-19 disease. The disease is a multisystem and mosaic disorder that demonstrates extra pulmonary manifestations involving liver and other organs. Elevated ... -
(4-{[(Pyridin-4-yl)methylidene]amino} phenyl)ferrocene
(Acta Crystallographica Section E, 2012)The asymetric unit of compound, [Fe(C5H5)(C17H13N2)], contains two independent molecules whose conformations differ, especially in the 4-{(pyridin-4 yl)methylidene]amino}phenyl unit where one is flipped by almost ... -
Synthesis and Characterization of Antiplasmodial Gallium (III) and Iron (III) Complexes of Aminochloroquinoline-3, 4- Hydroxypyridinone Conjugates: Preliminary Studies.
(INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN APPLIED SCIENCE, 2025)Metallation is a drug optimization strategy that has been used to enhance efficacy as well as pharmacokinetic and pharmacodynamic PK/PD properties in antimalarials. In our earlier studies antiplasmodial aminochloroquin ... -
Rapid Macronutrient Profiling of Maize Varieties Grown in Kirinyaga County, Kenya Using Atr-Ftir Spectroscopy and Chemometric Techniques.
(INTERNATIONAL JOURNAL OF RESEARCH AND INNOVATION IN APPLIED SCIENCE, 2025)Maize (Zea mays), a staple food in Kenya, is vital for food security and economic sustainability, contributing 12.65% to the agricultural GDP. Despite its centrality, limited studies have explored the nutritional ... -
Prioritised identification of structural classes of natural products from higher plants in the expedition of antimalarial drug discovery
(Natural Products and Bioprospecting, 2023)The emergence and spread of drug-recalcitrant Plasmodium falciparum parasites threaten to reverse the gains made in the fight against malaria. Urgent measures need to be taken to curb this impending challenge. The ... -
Leveraging off higher plant phylogenetic insights for antiplasmodial drug discovery
(Natural Products and Bioprospecting, 2023)The antimalarial drug-resistance conundrum which threatens to reverse the great strides taken to curb the malaria scourge warrants an urgent need to find novel chemical scaffolds to serve as templates for the development ... -
Kojic acid derived hydroxypyridinone–chloroquine hybrids: Synthesis, crystal structure, antiplasmodial activity and b-haematin inhibition
(Bioorganic & Medicinal Chemistry Letters, 2014)Aminochloroquinoline–kojic acid hybrids were synthesized and evaluated for b-haematin inhibition and antiplasmodial activity against drug resistant (K1) and sensitive (3D7) strains of Plasmodium falciparum. Compound 7j ... -
Discovery and Development of Antimalarial DrugResistance Reversal Agents
(Frontiers in Anti-Infective Drug Discovery, 2023): Despite the meritorious measures taken to curb the malaria scourge in the last two decades, the drug-resistance phenomenon threatens to reverse the gains made. Evidence of partial resistance against the first-line ... -
Development of a Traceability Model for Geographical Origin of Kenya’s Black Teas Based on Principal Component Analysis of FTIR and UV-Vis Spectral Data
(International Journal of research and innovation in applied science, 2025)Authentic tracing of the origins of black tea is important in the tea market as this helps to extrapolate the quality and thus prices. Tasting on its own can be a misleading test for tea quality and origin tracing since ... -
Analysis of Pesticide Residues in Tomatoes and French Beans from Murang’a and Kiambu Counties, Kenya
(European Journal of Nutrition & Food Safety, 2020)Poor Pesticide-handling practices during production of tomatoes and French beans pose adverse health and environmental effects. This study was conducted to determine the concentrations of pesticide residues in tomatoes ... -
Heavy Metal Concentration Levels In Surface Waters Of Lake Turkana And River Turkwel, Kenya
(IOSR Journal Of Applied Physics, 2025)Heavy metal contamination in surface waters is a significant global concern, particularly because people often settle near accessible water sources like lakes. This study examined the concentrations of heavy metals in ... -
Heavy Metal Concentration Levels in Some Selected Fish from Lake Turkana, Kenya
(International Journal of Research and Analytical Reviews, 2025)Heavy metal pollution in water poses a risk to both drinking water and fish consumed by people. This study aimed to assess how various heavy metals are distributed among different fish species. The study measured the ... -
Proximate Analysis and Physicochemical Properties of Oil from Four Avocado Cultivars from Murang’a County, Kenya
(American Journal of Chemistry, 2025)Avocado has a high nutritional value with a high content of unsaturated fatty acids, vitamins, phytochemicals, fiber, protein, and minerals such as magnesium and potassium. However, it is difficult to determine the ... -
Optimization Of Ph, Time, Yeast Substrate Ratio And Temperature For Production Of Bioethanol From Sweet Potato (Ipomoea Batatas) Peels
(IOSR Journal of Applied Chemistry, 2025)Introduction: The growing demand for renewable energy has led to increased interest in bioethanol production from non-food biomass. Sweet potato (Ipomoea batatas) peels, an agro-industrial waste, present a viable feedstock ... -
Influence Of Hydrochloric Acid Concentration On Reducing Sugar Yield And Fermentation Ph In Sweet Potato Peels Hydrolysis
(IOSR Journal of Applied Chemistry, 2025)Introduction: Acid hydrolysis remains one of the most effective methods for converting starchy and lignocellulosis feedstocks into fermentable sugars as compared to physical and thermal methods. This study determines the ... -
Synthesis and characterization of Ag-ZnO using citrus reticulata peel extract
(Material Research Express, 2025)To minimize the use of fossils fuels, solar cells have been considered to be effective despite facing major setbacks such as its cost and effectiveness. In this research Ag-ZnO was synthesized using Citrus reticulata as ...
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