Bioactive Constituents of Conyza floribunda

Show simple item record Opiyo, Sylvia A. Manguro, Lawrence O.A. Ogur, Joseph A. Wagai, Samuel Otieno 2017-10-05T10:52:05Z 2017-10-05T10:52:05Z 2010
dc.identifier.citation Research Journal of Pharmacology 4(3) : 55-59, 2010 en_US
dc.identifier.issn 1815-9362
dc.description DOI: 10.3923/rjpharm.2010.55.59 en_US
dc.description.abstract The study describes the antibacterial and antifungal effects of both CH2Cl2 and MeOH crude extracts, collected fractions and pure isolates of Conzya floribunda. The antimicrobial activity tests were carried out using agar diffusion method. In vitro tests using CH2Cl2 and MeOH extracts of C. floribunda showed anti-bacterial activities against Streptococcus pneumoniae, Staphylococcus aureus and Escherischia coli and antifungal activities against Candida albicans, Trichophyton mentagrophytes and Microsporum gypsium. The antibacterial and antifungal principles from C. floribunda were found to be (24S)-ethylcholesta-5, 22E, 25-dien-3-O-β-glucoside and cyasterone from methanol extract and 3-oxofriedooleanane and betullinic acid associated with CH2Cl2 extract. The results of the present study indicate that the plant could be a useful remedy for some of the disease conditions caused by the tested bacteria and fungi and the isolated compounds could be good candidates as phytotherapeutic agents some bacterial and fungal infections. en_US
dc.language.iso en en_US
dc.publisher Medwell Journals en_US
dc.subject Conyza floribunda en_US
dc.subject asteraceae en_US
dc.subject active principles en_US
dc.subject antimicrobial activity en_US
dc.subject bioactive constituents en_US
dc.subject Kenya en_US
dc.title Bioactive Constituents of Conyza floribunda en_US
dc.type Article en_US

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