Antiplasmodial flavonoids from Erythrina sacleuxii.

dc.contributor.author	Andayi, Andrew
dc.date.accessioned	2017-02-25T08:23:44Z
dc.date.available	2017-02-25T08:23:44Z
dc.date.issued	2005
dc.identifier.uri	http://hdl.handle.net/123456789/236
dc.identifier.uri	https://www.ncbi.nlm.nih.gov/pubmed/16491458
dc.description.abstract	Abstract The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acetone extract of the root bark afforded a new isoflavone, 7-hydroxy-4'-methoxy-3'-prenylisoflavone (trivial name 5-deoxy-3'-prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles. Flavonoids and isoflavonoids isolated from the stem bark of E. sacleuxii were also tested and showed antiplasmodial activities. The structures were determined on the basis of spectroscopic evidence.
dc.language.iso	en	en_US
dc.title	Antiplasmodial flavonoids from Erythrina sacleuxii.	en_US
dc.type	Article	en_US