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Antiplasmodial activity, in vivo pharmacokinetics and anti-malarial efficacy evaluation of hydroxypyridinone..
(2015)Background: During the erythrocytic stage in humans, malaria parasites digest haemoglobin of the host cell, and the toxic haem moiety crystallizes into haemozoin. Chloroquine acts by forming toxic complexes with haem ... -
Antiplasmodial activity, in vivo pharmacokinetics and anti‑malarial efficacy evaluation of hydroxypyridinone hybrids in a mouse model
(2016)During the erythrocytic stage in humans, malaria parasites digest haemoglobin of the host cell, and the toxic haem moiety crystallizes into haemozoin. Chloroquine acts by forming toxic complexes with haem molecules and ... -
Antiplasmodial activity, in vivo pharmacokinetics and anti‑malarial efficacy evaluation of hydroxypyridinone hybrids in a mouse model
(Dambuza et al. Malar J, 2015)Background: During the erythrocytic stage in humans, malaria parasites digest haemoglobin of the host cell, and the toxic haem moiety crystallizes into haemozoin. Chloroquine acts by forming toxic complexes with haem ... -
Antiplasmodial Flavonoids from Erythrina sacleuxii
(Planta Med, 2006)The acetone extracts of the root bark and stem of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic ... -
Antiplasmodial flavonoids from Erythrina sacleuxii.
(2005)Abstract The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. ... -
Application and control of flexible alternating current transmission system devices for voltage stability enhancement of renewable-integrated power grid: A comprehensive review
(Elsevier, 2021-03)This paper presents a comprehensive review on the application and control of Flexible Alternating Current Transmission Systems (FACTS) devices in order to improve voltage stability of power grid with high share of renewable ... -
Application of large-scale grid-connected solar photovoltaic system for voltage stability improvement of weak national grids
(Springer Nature Ltd, 2021-12)This paper investigates the application of large-scale solar photovoltaic (SPV) system for voltage stability improvement of weak national grids. Large-scale SPV integration has been investigated on the Nigerian power system ... -
Application of Mixture Experiments in Poultry Feed Formulation
(2018-12)The quality, components, proportions and storage of feeds is critical in poultry farming. The rising prices and poor quality of feeds has constantly led to low returns due to low final weights among birds. The study applied ... -
Application of Real-Time Deep Learning in integrated Surveillance of Maize and Tomato Pests and Bacterial Diseases
(Journal of the Kenya National Commission for UNESCO, 2024-01)With an emphasis on maize and tomato crops specifically, this research explores the creative fusion of computer vision (CV) and machine learning (ML) to address the enduring problem of pests and crop diseases impacting ... -
Application of Spritz Encryption in Smart Meters to Protect Consumer Data
(2019)The ongoing upgrade of the electrical power system into a more powerful system known as Smart Grid has both benefits and costs. Smart Grid relies on advanced communication and hence offers better services through improved ... -
An Appraisal of Financial Management Practices on the Growth of Micro Enterprise in Kenya
(Journal of Business and Economic Development, 2017)Governments in different parts of the world are increasingly promoting and supporting the growth of Micro and Small enterprises as part of their overall national development strategy. The sector plays an important role ... -
Approaches for Understanding Pastoral Response to Drought and Famine in Sub-Saharan Africa
(2016)Drought and famine in Sub-Saharan Africa is among the leading contributory causes of vulnerability in pastoral communities. This paper discusses approaches that allow understanding of pastoral indigenous adaptive ... -
Appropriateness of Liquidity Ratios Model in Predicting Shareholder Wealth of Non-Financial Firms Listed at Nairobi Securities Exchange, Kenya
(Research Journal of Finance and Accounting Vol.10, No.22, 2019, 2019)It is necessary that efforts are put in place by the global investing public to address the ever increasing need to accurately measure performance and financial strength of firms (Pandey, 2013). Analysts of financial ... -
Architecture and Tourism Perception, Performance and Place
(2015-11-04)The humanistic and social scientific study of tourism has an intriguing history. The largest peacetime movement of human beings in human history and a leisure time activity of the vast majority of academics, tourism, ... -
ASSESSING FACTORS ASSOCIATED WITH OBSERVED LEVELS OF ADHERENCE TO ANTIRABIES PEP VACCINE AMONG ANIMAL BITE VICTIMS IN MACHAKOS LEVEL FIVE HOSPITAL
(American Journal of Health, Medicine and Nursing Practice, 2017)Purpose: The purpose of this study was to determine factors associated with observed levels of adherence to ant rabies PEP vaccine among animal bite victims in Machakos level five hospital. Methodology: The study used ... -
Assessing the Drivers of Enhanced Auditors Performance: A Case Study in Public Universities in Kenya
(2021-06)The study evaluated the key drivers of enhanced auditor’s performance in public universities in Kenya. The study posits that work environment, auditor’s competence, independence and authority have not significant effects ... -
Assessing the Effects of M-Shwari on Financial Inclusion among Muhoroni Factory Sugarcane out - Growers’ Households in Muhoroni Sub-County, Kenya
(European Journal of Business and Management . Vol.8, No.19, 2016, 2016)In Kenya today the decline in cane production per given unit area has led to a domestic sugar consumption deficit that averages 200,000 tonnes of sugar annually. An aggressive financial inclusion strategy in the sugar ... -
Assessing the potential of camel milk as a livelihood option in the face of climatic and environmental changes in drylands of Kenya
(2012)In drylands of Kenya, the adverse effects of climate variability and change has directly weakened the pastoral production system and made it less effective as a livelihood option. This has med most pastoral household food ... -
Assessment Framework for Cyber Security
(LAP Lambert Academic Publishers, 2016)The capabilities and opportunities the Internet provides have caused transformation in many business activities, increasing the speed and ease for conducting transactions while also lowering many of the costs. As a ...